Prescription Drug
Overdose Deaths
in Southwest Virginia, 2003
John Dreyzehner, MD, M.P.H.
Director, Cumberland Plateau Health District
Photo Courtesy Tim Cox
This presentation deals not with an outbreak investigation, but rather what appears to be an emerging epidemic.

Background: Prescription drug abuse has been an escalating problem over the past decade in Virginia. Corresponding to the increase in persons abusing prescription drugs has been an increase in fatalities among that population group. In Southwest Virginia, the number of drug related deaths increased by over 300 percent between 1993 and 2003. Objectives: Epidemiologically describe the population dying from prescription drug overdose and the drugs associated with these deaths.  Methods: A chart review of all deaths attributed to a prescription drug overdose in the Western District of the Office of the Chief Medical Examiner.  Data was entered into EpiInfo v3.2, and descriptive analysis was done utilizing SPSS v11.0 and ArcView 8.3. Results: A total of 211 charts were reviewed. The manner of death was classified as accidental in 79.6 percent and suicide in 18.0 percent of cases.  Of those accidental deaths the majority were white, male, and married with an average age of 36.8 years. History of depression and/or chronic illness was indicated in 38.7 and 39.9 percent of cases respectively. Opioid pain medications were most frequently associated with accidental overdose; Methadone accounting for 44.6 percent and hydrocodone 16.1 percent of those deaths. Conclusion: The finding of narcotic pain medication in the increasing number of overdose deaths is consistent with findings by other investigators.  Education of providers, patients and the public regarding the risk of abuse and misuse of these narcotic pain medications, their pharmokinetic properties and associated risks, among other things, could lead to a reduction in mortality.